Why Are My Dog’s cPL Test Results High?

Ron Hines DVM PhD

This is a test designed for dogs. If you pet is a cat, go here

To see what normal blood and urine values are, go here

For an explanation of causes of most abnormal blood and urine tests, go here

To see how tests are grouped, go here

If your pet is a cat, go here

This is not your pet’s serum lipase level. For that , go here

cPL The SNAP® cPL™ Test

aka PLI, Canine Pancreas-specific Lipase Test, Pancreatic Lipase Immunoreactivity

This test was designed specifically for dog. A similar one, the cPL test was designed for cats.

Veterinarians have tracked total blood lipase levels in dogs for a long time. They knew that the level of that digestive enzyme , necessary to absorb certain fats (triglycerides), often went up in dogs when they had pancreatitis. But lipase-like compounds are not only produced in your pet’s pancreas, the dog’s liver, adrenal glands and blood vessels also produce some. So a high total blood lipase levels might truly indicate pancreatitis; but they might also indicate intestinal . The cPL (for dogs) or the cPL (for cats) are thought to be better at zeroing in on pancreatic problems and crossing out intestinal problems from the diagnosis. That is very important because treatment options for the two are different – as are the suggested diets to prevent your dog from relapsing.

The test is often performed to try to explain the cause of sudden bouts of vomiting, depression, abdominal pain and a decreased interest in food.

The test is not perfect, but it gives accurate results about 80% of the time.

Complimentary Tests:

CBC/WBC and blood chemistry profile including PCV, TP, glucose and electrolytes, urinalysis, x-ray/ultrasound, FIV /FLV test if a cat, T4 if the cat over 6 years old, cobalamin, folate, fecal examination


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