Corticosteroids Such As Prednisone Increase Appetite And Fluid Retention

Ron Hines DVM PhD

Back to chubby pets article   

Although the vast majority of overweight dogs and cats are healthy pets that got that way because of their lifestyles, there are some that gain weight because they have to receive medications to control serious diseases. Those are the dogs and cats receiving corticosteroid medications like prednisone, prednisolone, methylprednisolone, etc. on a regular basis (all end in –sone). Some of those are pets that have severe skin allergies (canine and feline atopy), others have chronic inflammations of their intestinal tract (inflammatory bowel disease=IBD, Triad disease, etc.), some have cancers of the immune system (eg lymphoma) and others have autoimmune disease in the lupus group. Any pet receiving those medications in significant amounts over extended periods of time will have the urge to eat more and, if the extra food is there, gain weight. Although much of that added weight is fat, some of it is fluid (edema ) and some is liver enlargement.  Pete and Repeat’s article pertains to those pets on steroids too. 

Corticosteroids also increase your dog and cat’s thirst. So it will drink and pee more and perhaps have urination accidents. But never be tempted to restrict your pet’s access to water during daytime hours – that can cause dangerous dehydration. 

You are on the Vetspace animal health website